Resveratrol Research

The Link Between Resveratrol and Longevity Article written for Vera Roasting Co.

Article Written by: Talha Ahmad RDN

Resveratrol is a polyphenolic chemical found in plants that serves to shield plants from the damaging effects of UV radiation and other environmental stresses. In animals, resveratrol functions as an antioxidant and has a number of positive health effects, including decreasing cholesterol and improving general health.

Red wine, grapes, berries, peanuts, and peanut butter are typical resveratrol food sources. 

Numerous studies have demonstrated that resveratrol can lengthen an animal's life span. Resveratrol has neuroprotective, cardioprotective, antidiabetic, and anticancer effects on the body in addition to being linked to an improvement in general health. In this post, we'll explore the relationship between resveratrol and lifespan as well as some of its other potential health advantages.

What Does the Science Say?

The science of medicine has been fascinated by the question of how to lengthen life, and resveratrol has played a significant role in many of these investigations. According to research, resveratrol turns on the genes that protect against aging-related diseases. Resveratrol's anti-aging effects function similarly to calorie restriction. A study of studies on various animals indicated that 60 percent of the animals had the impact of an extended life span. All of this research was carried out on animals, and it is yet unknown whether this substance will have the same effect on humans.

However, research has revealed a wide range of other resveratrol-related potential health advantages that may increase longevity.

Lowers blood pressure: Resveratrol can help decrease blood pressure and contains some antioxidant benefits. High doses of resveratrol have been shown to lower the systolic blood pressure in arteries when the heart beats, according to a review of numerous research published in 2015. The highest reading on blood pressure readings is systolic blood pressure. Age-related artery stiffening and an increase in systolic blood pressure are both risk factors for heart disease. Nitric oxide generation is aided by resveratrol. Nitric oxide decreases blood pressure and aids in the relaxation of blood vessels.

Lowers bad cholesterol: Numerous animal studies have indicated that resveratrol administration can aid in the proper management of blood cholesterol. In a 2016 study, mice were fed a diet high in polyunsaturated fats and protein with resveratrol supplementation. According to the study, resveratrol administration caused mice's body weight and total cholesterol levels to drop while raising their levels of good cholesterol. The impact of the enzyme that increases cholesterol synthesis is lessened by resveratrol. Resveratrol functions as an antioxidant and prevents LDL from oxidizing. Our blood arteries develop plaque as a result of LDL oxidation.

Protects the brain: Red wine consumption has been demonstrated in numerous studies to slow the pace of cognitive decline as people age. The antioxidant resveratrol can prevent Alzheimer's disease by interfering with beta-amyloid protein fragments. Resveratrol is a substance with anti-inflammatory and antioxidant characteristics that claims to be able to shield brain cells from harm.

Increases insulin sensitivity: Resveratrol has been proven in animal studies to help enhance insulin sensitivity and help reduce diabetes complications. A specific enzyme converts glucose to sorbitol. Resveratrol prevents that enzyme from functioning. An excessive amount of sorbitol in the body of diabetics might harm cells through oxidative stress. Resveratrol has antioxidant and anti-inflammatory qualities that can help diabetics avoid the disease's inflammatory and oxidative consequences. A protein called AMPK, which is activated by resveratrol, aids in the breakdown of sugar and maintains normal blood sugar levels.

Protects against cancer: To examine resveratrol's capacity to fight cancer has been tested in test tubes. Studies on animals and in test tubes have demonstrated that it can combat a number of malignancies, including breast, prostate, skin, stomach, colon, and skin cancers. Cancer cells' ability to grow, divide, and spread can be slowed down by resveratrol. It has the ability to alter gene expression and stop the development of cancer cells. Hormone-related malignancies can be avoided thanks to resveratrol's effect on hormones.

Conclusion

A polyphenolic substance known as resveratrol has strong anti-inflammatory and antioxidant effects. It can lengthen life and promote longevity, according to research conducted on animals. In addition to this result, resveratrol has additional health advantages that aid increase life span and quality. The primary causes of death include diabetes, hypertension, heart disease, and cancer, and the anti-inflammatory and antioxidant qualities aid in their prevention.

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Posted by: Kate Putnam
October 2, 2022
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